The Dutch government has decided to allow only tobacco-flavored e-cigarettes to be placed on the market, and urged the National Institute for Public Health and the Environment (RIVM) to conduct a risk assessment of an exhaustive list of 23 tobacco-flavored substances, which it intends to make legal in future e-liquids. List of flavor additives. RIVM recently released the "Health Effects of 23 Flavor Substances in Electronic Cigarette Liquid" evaluation report, further reducing the number of flavor substances to be approved to be added to 16.

In this issue, we will interpret the main content of the report to help you clearly understand the progress of e-cigarette flavor restrictions in the Netherlands.

RIVM assessment findings

a. Isophorone (78-59-1) and pyridine (110-86-1) may be carcinogenic;

b. β-Caryophyllene (87-44-5) may cause respiratory allergy;

c. p-cresol (106-44-5) may cause respiratory irritation;

d. Tobacco ketone (13215-88-8), trimethylpyrazine (14667-55-1) and 2-ethyl-3-methylpyrazine (15707-23-0) in some e-liquids Concentrations are very high and may result in increased systemic health risks in intensive users.

RIVM assessment conclusion

a. For the above 7 substances, RIVM recommends that they be prohibited from being used in e-liquids;

b. For the remaining 16 substances, due to insufficient information to assess the health risks posed by their use in e-cigarettes, RIVM recommends either banning these substances according to the precautionary principle (strictly), or allowing the use of these substances in e-liquids .

List of the remaining 16 substances

At present, the expected control trend of e-cigarettes in the Netherlands is to restrict flavors to protect young people and non-smokers. It is recommended that relevant export companies pay close attention to the regulations of EU member states to ensure smooth and compliant exports.

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